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高浓度静脉补钾的临床探讨 被引量:14

A CLINICAL STUDY ON INTRAVENOUS CONCENTRATED POTASSIUM INFUSION THERAPY
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摘要 对重症监护病房接受高浓度静脉补钾的50例临床资料进行分析.浓度80-400mmol/L的氯化钾溶液以低于或等于20mmol/L的速度经中心静脉输注共123次,以纠正低钾血症.结果显示,采用此方法补钾能有效地提高血钾水平.但血钾浓度提高值与补钾剂量间无显著直线相关.发现6次高钾血症,发生在肾功能衰竭或补钾前血钾正常者.未发现致命性严重心律失常.结果表明,这种高浓度静脉补钾的治疗方法在监护病房是相对有效、安全的,但需合理应用,尤其在肾功能损害时要谨慎使用.这种治疗方法在急危重病的抢救中有一定临床价值. The records of 30 patients admitted to our Intensive Care Unit who received intravenous infusions of concentrated potassium chloride were analyzed. A total of 123 times of infusions, with potassium concentration 80 to 400 mmol/L, were administered by the central venous route at the rate equal to or less than 20 mmol an hour for correcting or preventing hypokalemia. The results showed that serum potassiun level could effectively be increased and hypokalemia could be corrected in the majority of the patients after the infusion were administered. No significant linear correlation could be shown between incremental potassium concentration and potassium dose administered. There were 6 instances of hyperkalemia,which happened in those patients with renal failure or having normal initial potassium levels. No related life-threatening arrhythmias were noted. The results indicate that the therapy of potassium replacement using concentrated (80 to 400mmol/L) potassium chloride infusions at the rate ≤20 mmol an hour via central vien was relative effective and safe in patients in the Intensive Care Unit) However , it must be used properly, especially carefully in patients with diminished renal function. This therapy is , on certain conditions, of clinical value in treating critically ill patients.
出处 《急诊医学》 CSCD 1997年第1期25-28,共4页
关键词 氯化钾 补钾 低钾血症 心律失常 肾功能衰竭 Potassium chloride Hypokalemia Hyperkalemia Arrhythmia Renal failure
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