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脑梗塞患者急性期血清SOD、MDA变化

THE CHANGING IN SERUM SOD、MDA DURING ACUTE CEREBRAL INFARCTION PATIENTS.
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摘要 对80例脑梗塞急性期病人分别测定血清中过氧化脂质代谢产物丙二醛(MDA)及体内重要的自由基清除剂超氧化物歧化酶(SOD)的活性,发现脑梗塞急性期血清MDA明显增加而SOD活性明显降低,二者成负相关,结果提示脑梗塞急性期自由基参与了脑损伤机制。 In order to determine the serum activities of malondialdehyde(MDA),a metabolite from lipid peroxide and of superoxide dismutase(SOD),an essential scavenger of free radical in the body,80 cases of acute cerebral infarction patients have been respectively detected and thus,it is found that during acute cerebral infarction serum MDA goes up obviously wherase SOD activity comes down,showing a negative correlation between these two.The result displays that free radicals takes part in the mechanism of brain damage in the period of cerebral infarction.
出处 《现代预防医学》 CAS 1997年第1期59-60,共2页 Modern Preventive Medicine
关键词 脑梗塞 自由基 丙二醛 超氧化物歧化酶 Cerebral infarction Free radical Malondialdehyde(MDA) Superoxide dismutase(SOD)
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