摘要
研究建立了肝癌特异GGT免疫测定法。结果阳性OD值≥0．267（—2S）；阴性OD值≤0．065（x＋2S）；肝癌病人血清OD值比正常人高4～11倍。批内及批间CV分别为4．85％和6．27％。初步应用结果显示，对原发性肝癌（PHC）诊断阳性率为86．79％；特异性为94．72％；对继发性肝癌（MHC）诊断阳性率为42．86％；早期诊断阳性率为57．14％。
Immunoassay specifically for serum y-glutamyltranspeptidase in hepatocellular cancer patients has been established and used in the author' s institution. The positive and negative OD value in sera were 0. 267(x-2s) and 0. 065 (x+2s) respectively. OD values in sera of patients with primary hepatocellular carcinoma (PHC)were 4 - 11 times higher than those in healthy controls. The CV values within batch and between batches were 4. 85% and 6. 27% respectively. Preliminary results showed that the positive rate was 86. 79% for PHC and 42. 86% for metastatic cancer in liver. The positive rate was 57. 14% for early stage cancer with a specificity rate of 94. 72%. This new technic is not only sensitive and specific,but also serves as a simple and rapid means for laboratory diagnosis.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1997年第6期444-447,共4页
Chinese Journal of Clinical Oncology
