摘要
目的：对比研究调强适形放疗（IMRT）、三维适形放疗（3DCRT）和常规模拟机定位放疗等3种不同方法在食管癌术后预防照射中的优缺点.方法：15例食管癌术后患者采用IMRT方法进行治疗,应用同一治疗计划系统,制订模拟适形放疗和常规模拟机定位放疗方案,3种方案照射剂量均为1.8～2.0Gy/次,5次/周,50Gy/5～6周.结果：与3DCRT和常规模拟机定位放疗相比,食管癌术后照射中IMRT有最好的剂量分布,既可明显提高靶区的剂量,同时能较好地保护正常组织. 结论：食管癌术后采用IMRT优于3DCRT和常规模拟机放疗,是目前最佳的一种放疗方法.
Objective：To assess and compare the advantages and disadvantages of postoperative intensity modulated-radiation therapy （ IMRT）, 3-Dimensional conformal radiation therapy （ 3 DCRT） and the simulator-guided radiation therapy for patients with esophageal carcinoma. Methods：Fifteen patients with postoperative esophageal carcinoma were treated by intensity modulated-radiation therapy, at the same TPS, 3-Dimensional conformal radiation therapy target and normal tissue of three radiotherapies were simulated. The treatment planning was five days per week with 1.8 - 2.0 Gy/fraction, 5 fractions/week, 50 Gy/5 -6 weeks. Results：Compared with simulator-guided radiation therapy and 3DCRT. IMRT planning has better dose distribution and protection of normal tissue. Conclusion：IMRT was better than 3DCRT and simulator-guided radiation therapy.
出处
《医学研究生学报》
CAS
2007年第8期838-840,共3页
Journal of Medical Postgraduates
基金
南京军区南京总医院科研基金资助项目(批准号:2004027)
关键词
调强适形放疗
三维适形放疗
常规模拟机定位放疗
Intensity modulated-radiation therapy
3-Dimensional conformal radiation therapy
Simulator-guided radiation therapy
