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单克隆抗体药物在恶性肿瘤靶向治疗中的应用

Monoclonal antibodies in the targeted therapy of malignant neoplasms
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摘要 肿瘤分子靶向治疗研究进展迅速，单克隆抗体（MoAb）是其中的重要组成部分。由于其特异性高，性质均一，在许多恶性肿瘤治疗中表现出高效低毒的优势，开辟了肿瘤治疗新途径。大多数单抗类药物与传统化疗有协同作用，其疗效较单纯化疗显著提高。 The molecular targeted therapy develops rapidly and monoclonal antibody drugs （MoAbs） are one of the important components. Because of high specificity and homogeneous nature, MoAbs demonstrate a profile of high efficacy and low toxicity in many malignant neoplasms therapy , and which opens up a new avenue of cancer treatment. Most moneclonal antibody drugs have synergies with conventional chemotherapy, and can enhance efficacy significantly compared with chemotherapy alone.
作者 刘志芳 郭其森（综述）
机构地区 山东省肿瘤医院内一科
出处 《国际肿瘤学杂志》 CAS 2007年第7期487-490,共4页 Journal of International Oncology
关键词 抗体 单克隆 免疫毒素类 抗肿瘤药 肿瘤 Antibodies, monoclonal Immunotoxins Antineoplastic agents Neoplasms
分类号 R730 [医药卫生—肿瘤]
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参考文献23

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国际肿瘤学杂志
2007年 第7期

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