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糖尿病性白内障危险因素探讨 被引量:8

A CASE-CONTROL STUDY ON RISK FACTORS OF DIABETIC CATARACT
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摘要 [目的]探讨糖尿病性白内障的危险因素。[方法]采用以医院为基础的成组病例对照研究方法,对研究对象进行问卷调查,其中病人86例,对照121例。资料分析采用非条件Logistic回归。[结果]年龄(OR=2.941,95%CI:1.835-4.714)、糖尿病病程(OR=1.721,95%CI:1.102-2.687)、白内障家族史(OR:5.724,95%CI:1.784-18.366)、血糖监测次数少(OR=1.944,95%CI:1.094-3.455)、高糖化血红蛋白水平(OR=2.475,95%CI:1.450-4.223)、糖尿病视网膜病(OR=5.725,95%CI:2.458-13.336)、血浆胆固醇水平增高(OR=2.616,95%CI:1.473-4.647)、患糖尿病后油脂类食物摄入过多(OR=4.344,95%CI:1.483-12.720)与糖尿病性白内障的发生相关。[结论]在糖尿病人群中,年龄,病程长、白内障家族史、血糖监测次数少、高糖化血红蛋白水平、糖尿病视网膜病变、血浆胆固醇水平增高、DM后油脂类食物摄入过多可能是糖尿病性白内障发生的危险因素。 [Objective] To investigate the risk factors of diabetic cataract. [Methods] A hospital-based case-control study was conducted .86 diabetic cataract patients and 121 DM patients without cataract were selected as case group and control group respectively. Information was obtained by questionnaires.Univariate Logistic regression, multivariate Logistic regression were used to analyse the risk factors and the potential interactions for some risk factors. [Results] Age (OR=2.941, 95% CI: 1.835-4.714) , longer duration of DM (OR=1.721, 95%CI: 1.102-2.687) , the family history of cataract (OR = 5.724, 95%CI: 1.784-18.366), less blood sugar testing (OR: OR=1.944, 95%CI: 1.094-3.455), high level of GhbA1C% (OR = 2.475, 95%CI: 1.450-4.223), diabetic retinopathy (017=5.725, 95%Ch 2.458-13.336), high level of plasma cholesterol (OR=2.616, 95%Ch 1.473-4.647) , more intake of lipidic food after diabetes mellitus (OR=4.344, 95%CI: 1.483-12.720) were related to diabetic cataract. [Conclusion] The main risk factors of diabetic cataract ale age, longer duration of DM, the family history of cataract, less blood sugar testing, high level of GhbA1C%, diabetic retinopathy, high level of plasma cholesterol and more intake of lipidic food.
作者 柳剑 蓝绍颖
出处 《现代预防医学》 CAS 北大核心 2007年第15期2837-2838,共2页 Modern Preventive Medicine
关键词 糖尿病性白内障 危险因素 成组病例对照研究 LOGISTIC回归 Diabetic cataract Risk factors Case-control study Logistic regression
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