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前列腺增生手术前后膀胱重量变化的研究 被引量:4

Study on the change of bladder wall weight pre and after surgery in patients with benign prostatic hyperplasia
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摘要 目的探讨良性前列腺增生(BPH)经尿道前列腺切除术(TURP)手术前后膀胱重量的变化及临床意义。方法 BPH 患者63例,其中术后随访资料完整者21例,以相同年龄段无下尿路症状30例男性作为对照组。经腹 B 超测量膀胱壁厚度并结合膀胱容量按照球形体积公式估算膀胱重量。以尿动力学检查评价膀胱出口梗阻(BOO)和膀胱功能。63例 BPH 患者术前膀胱重量(97±54)g,对照组为(41±14)g,膀胱重量与梗阻分级(LinPURR)呈正相关(R=0.47),与最大尿流率(Qmax)呈负相关(R=-0.52),与残余尿量呈正相关(R=0.48),差异均有统计学意义(P<0.01),与逼尿肌收缩强度(WF)呈负相关(R=-0.40,P<0.05)。21例患者术前 B 超估测膀胱重量(UEBW)(99±50)g。结果 21例患者术后 UEBW 为(56±21)g,与术前比较差异有统计学意义(P<0.01)。术后 UEBW 平均下降43.68%,国际前列腺症状评分(IPSS)下降16.81分,Qmax 平均增加8.38 ml/s。结论膀胱重量作为一项无创性检查方法,对前列腺增生症进展的监测、术前评估和术后疗效的评价具有临床应用价值。 Objective To investigate the changes and its clinical significance of ultrasound evaluated bladder wall weight(UEBW) pre and after surgery in patients with benign prostatic hyperplasia (BPH). Methods The clinical data of 63 patients of benign prostatic hyperplasia and 30 of contrast control were studied. The bladder wall weight was calculated by subtracting the volume of sphere represented by the urine volume inside the bladder from the volume of the sphere representing the whole bladder ( sphere with a radius = internal radius + baldder wall thickness). Bladder outlet obstruction(BOO) and bladder function was evaluated by urodynamic studies. Of the 63 patients with BPH, UEBW was (97 ± 54) g, while the control group was only (41 ± 14) g. UEBW was found to be significantly correlated with LinPURR grade(R =0.47,P 〈0.01) and postvoid residual urine volume (R =0.48, P 〈0.01), and it was negtlvely correlated with Qmax (R = -0. 52 ,P 〈 0. 01 ) and detrusor contraction strength (presented as WF, R = - 0. 4, P 〈 0. 05 ). Results A significant difference was found between the UEBW pre and after sugery [ ( 99 ± 50) g vs. (56 ± 21 ) g, t = 5. 05, P 〈 0. 01 ) ]. UEBW decreased 43.68%, and IPSS score decreased 16. 81 point, while Qmax increased 8. 38 ml/s. Conclusion As an non-invasive methods, measurement of bladder wall weight appears to be a useful marker in evaluating status before operation and in monitoring the effection of surgery for patients with BPH.
出处 《中华外科杂志》 CAS CSCD 北大核心 2007年第14期954-956,共3页 Chinese Journal of Surgery
关键词 前列腺增生 器官重量 膀胱 膀胱出口梗阻 Prostatic hyperplasia Organ weight Bladder Bladder outlet obstruction
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参考文献8

  • 1Kojima M, Inui E, Ochiai A, et al. Ultrasonic estimation of bladder weight as a measure of bladder hypertrophy in men with infravesical obstruction: a preliminary report. Urology, 1996, 47 : 942-947.
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