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百日咳毒素在疫苗中的研究现状及应用 被引量：2

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摘要 百日咳毒素（PT）是百日咳杆菌所产生的主要毒力因子，具有多种生物学活性，是无细胞百日咳疫苗中唯一不受争议的抗原成分。随着分子生物学技术的发展，研究者试图开发与PT有关的重组亚单位疫苗、重组细菌疫苗和DNA疫苗。本文对近年来的研究进展作一综述。
作者 杨瑜（综述） 朱为（审校）
机构地区 上海生物制品研究所第三研究室
出处 《国际生物制品学杂志》 CAS 2007年第4期156-159,共4页 International Journal of Biologicals
关键词 百日咳 百日咳毒素 百日咳菌苗
分类号 R378.42 [医药卫生—病原生物学]
  • 相关文献

参考文献23

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二级参考文献11

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共引文献20

同被引文献13

  • 1张庶民,徐颖华.我国百日咳疫苗现状及展望[J].中国药事,2005,19(11):685-688. 被引量：15
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  • 3侯启明,张路民,梁雅文,秦进才.应用CHO细胞法检测百日咳疫苗中的残余毒性[J].中国生物制品学杂志,1997,10(2):101-103. 被引量：4
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引证文献2

二级引证文献5

国际生物制品学杂志
2007年 第4期

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