摘要
目的观察参芪扶正液联合化疗对非小细胞肺癌患者外周血细胞水平及免疫细胞活性的影响。方法选择Ⅲ～Ⅳ期非小细胞肺癌患者采用TP方案联合参液扶正液治疗34例,与单用TP方案28例进行治疗前后T细胞亚群及NK细胞活性的检测与比较,并比较两组的血液毒性反应。结果治疗组其细胞免疫能力不同程度提高,而对照组免疫能力下降,两组有显著性差异;前者血细胞无明显下降,毒副反应较轻,生活质量明显改善。结论参芪扶正注射液可作为晚期肺癌化疗的辅助用药以提高机体免疫功能,降低化疗后毒副反应的发生率。
Objective： To observe the clinical effects of cellular immunity state of body and toxic effect of the treatment by chemotherapy combined with Shenqi -fuzheng injection used for non small cell lung cancers （NSCLC）. Methods： 34 cases with NSCLC were given Shenqi - fuzheng injection combined with TP chemotherapeutic protocol （group A）, 28 cases were given TP chemotherapy only（group B）. The ability of T cell and NK cell were examined in both group after treatment, and the toxic effect were also been compared. Results： The ability of immunocyte was improved in group A, while it was weakened in group B. There was statistical significance. Compared with group B, group A had lower toxic effects. Conclusion： Shenqi - fuzheng injection can improve the ability of immunity of body and reduce toxic effects when used in advanced NSCLC.
出处
《中国中医急症》
2007年第7期776-777,共2页
Journal of Emergency in Traditional Chinese Medicine
