摘要
以HFRS疫苗人工免疫健康个体，经免疫荧光技术检测，在人血片白细胞中可检出HFRS病毒特异性抗原。血片白细胞特异性抗原在初次免疫7d后，阳性率为100％，强阳性率为77.7％，再次免疫7d后，强阳性率高达88.8％，但当继续加强免疫后，抗原阳性率及强阳性率均下降。在检测血片白细胞中抗原的同时，检测血清中特异性抗体，结果初次免疫7d后，低滴度抗体阳性率为88.8％，强阳性率仅为22.2％。
Immunofluorescence technige was used to detect the specific antigen of Hemorrhagic fever with renal Syndrome (HFRS) virus in white blood cell of the normal human immunized with HFRS vaccine. The postive rate of specific antigen in white blood cell was 1oo%,and the strong postive rate was 77. 7% 7 days after first vaccination;after the second immunization,the strong postive rate was 88. 8%.But when immunizing them once again, the postive and strong postive rates declined. The specific antibody was also measured at the same time. The result showed that the postive rate of specific antibody was 88. 8% and the strong postive rate was 22. 2% 7 days after first vaccination.
出处
《合肥医学院学报》
1997年第1期26-28,共3页
Journal of Zunyi Medical University
