摘要
目的 对液基超薄技术(thinprep cytologic test,TCT)和Betheasda系统(TBS)在宫颈病变诊断中的临床应用价值进行评价。方法 2005年12月~2006年5月对在体检中心就诊的635例体检者行TCT检查和TBS细胞学分类诊断,对TCT检查发现异常的患者进行阴道镜病理检查和HCⅡHPV检测。结果 635例涂片中检出异常涂片66例(10.23%),其中不典型鳞状细胞(ASCUS)37例(5.83%),低度鳞状上皮内病变(LSIL)18例(2.80%),高度鳞状上皮内病变(HS|L)10例(1.57%),鳞状细胞癌(SCC)1例(0.16%)。TCT与阴道镜病理检查和HCⅡ检测的符合率是92.95%、87.00%。结论 TCT技术结合TBS应用于宫颈细胞涂片配合HPVDNA检测和阴道镜活检,是筛查和诊断子宫颈癌前期病变的可靠手段。
Objective To evaluate the clinical value of thinprep cytologic test(TCT) and the Bethesda system(TBS) for the diagnosis of early cervical diseases. Methods A total of 635 patients in our hospital had been examined by TCT and TSB from December 2005 to 2006. the abnormal cases which had been selected by TCT were detected by colposcopical pathological examination and Hybrid Capture lI HPV testing. Results We found 66 ( 10.23% ) abnormal smears out of 635 cases, in which atypical squamous cell of undetermined significance (ASCUS) 37 cases (5.83%) , low grade squamous intraepithelial lesion (LSIL) 18cases(2.80% ) , high grade squamous in- traepithelial lesion (HSIL) 10 cases ( 1.57% ) , quamous cellcarcinoma 1 case(0.16% ). The rates of coordinance with pathological results of colposcopy and HC Ⅱ were 92.95% and 87.00% respectively. Conclusions TCT and TBS,sometimes combined with the colposcspy and HPV DNA test,may be a reliable method to screen and diagnose the precancerosis of cervix.
出处
《医学研究杂志》
2007年第7期102-104,共3页
Journal of Medical Research
关键词
宫颈涂片
液基超薄细胞技术
TBS系统
Cervial smesrs
Thinprep cytologic test
Betheasda system
Human papilloma virus