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2型糖尿病合并高血压患者左心室结构和功能变化 被引量:1

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摘要 目的探讨2型糖尿病患者在并发或不并发高血压时的心脏结构和功能的变化。方法2型糖尿病98例,依血压水平分为单纯2型糖尿病组50例,2型糖尿病合并高血压组48例,对照组30例为体检健康者。观察血糖、血脂、体重指数,应用超声心动图仪检测左心室结构和功能。结果与对照组相比,2型糖尿病患者有糖、脂代谢异常(P<0.05),3组之间左心室舒张末内径(left ventricular end diastolic dimension,LVEDd)、室间隔厚度(interventricular septum thickness,LVST)、左心室后壁厚度(left ventricular posterior wall thickness,LVPWT)及左心室质量指数(left ventricular mass index,LVMI)差异有统计学意义(P<0.05),2型糖尿病合并高血压组明显高于其他两组(P<0.05),3组间舒张早期血流充盈峰值流速E值及E/A比值差异无统计学意义(P<0.05),2型糖尿病合并高血压组下降更明显;与对照组相比,2型糖尿病合并高血压组的左心室射血分数(left ventricular ejection fraction,LVEF)、左心室短轴缩短率(fractional shortening,FS)下降(P<0.05)。结论2型糖尿病患者存在左心室结构及功能受损,随血压升高,这些改变更为明显。
出处 《岭南心血管病杂志》 2007年第3期214-216,共3页 South China Journal of Cardiovascular Diseases
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参考文献8

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