摘要
目的：探讨肠内给予极低出生体重儿谷氨酰胺（Gln）对其生长发育，胃肠功能及感染发生率的影响。方法：将34例极低出生体重儿随机分为治疗组和对照组，治疗组在给予PN的同时，经肠道给予Gln，对照组常规PN、监测两组生长发育、喂养耐受情况，胃肠功能及感染发生率。结果：治疗组生后4周时，尿素氮（BUN）水平较对照组高（P〈0．05），但仍在正常范围内。平均PN时间及平均住院时间均短于对照组（P〈0．05）。感染发生率较对照组明显减少（P〈0．01）。结论：初步观察提示，经肠道给予极低出生体重儿Gln，对其生长发育，胃肠功能的成熟及减少院内感染的发生是有益的。
Objective To investigate the effects of glutamine-supplemented feeding in very low birth weight infants（YLBW） on growth and development, gastrointestinal function, and the incidence of infectious episodes. Methods Thirty-four very low birth weight infants were assigned to two groups randomly, two groups were received parenteral nutrition（PN）, the glutamine group received additionally glutamine feeding. （glutamine took 20% of amino acid intake at the given day）. The differences in growth and development, enternal feeding tolerance, gastrointestinal function and infectious episodes in two groups were monitored and compared. Results serum blood urea nitrogen was higher in glutamine group 4 weeks after birth （P〈0.05）,but still normal range. The average PN duration and hospitalization period were significantly shorter in glutamine group （P〈0.05） The infection episodes of glutamine group were less than those in control group（P〈0.01）. Conclusions Our initial proves that glutamine supply is helpful to the maturation of the gastrointestinal function and decrease of nosocomial infection incidence.
出处
《国际医药卫生导报》
2007年第14期83-86,共4页
International Medicine and Health Guidance News
