摘要
目的：了解院内下呼吸道感染的发生和分布，为临床合理选择抗菌药物提供参考。方法：回顾性调查我院2004年1月～2006年12月380例下呼吸道感染患者痰标本细菌培养分离及药敏试验结果，分析病原菌的耐药性及抗菌药物使用情况。结果：共培养出18种病原菌，检出252株，革兰阴性菌占72．6％，革兰阳性菌占23．4％，真菌占4．0％。结论：我院抗菌药物应用总体较为合理，但仍存在一些不合理之处，包括给药剂量、次数、联合用药种类搭配不当、更换药间隔时间过短等，亟待采取有效措施予以干预。
OBJECTIVE：To investigate the occurrence and distribution of hospital lower respiratory tract infections in our hospital so as to provide a reference for the rational use of antibacterials in the clinic.METHDOS： 380 patients with lower respiratory tract infections hospitalized in our hospital from Jan .2004 to Dec .2006 were reviewed retrospectively in respect of the results of sputum culture and antimicrobial susceptibility,and the drug resistance of pathogens and the use of antibacterials were analyzed.RESULTS： A total of 252 strains（18 kinds） were detected, of which, 72.6% were gram-negative bacterium, 23.4% were gram - positive bacterium, and 4.0 % were fungi. CONCLUSION.. On the whole, the use of antimicrobial agents in our hospital is rational, yet there are still some problems existed,which include the irrationality in dosage and number of times of medication,inappropriate drug combination and frequent change of antimicrobial agents etc.Therefore, effective measures are urgently needed to tighten controls on the use of antimicrobial agents.
出处
《中国药房》
CAS
CSCD
北大核心
2007年第20期1538-1540,共3页
China Pharmacy
关键词
院内下呼吸道感染
病原菌
合理用药
Hospital lower respiratory tract infection
Pathogen
Rational use of drugs
