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非小细胞肺癌后程加速超分割放疗协同化疗的疗效分析

Late-course Accelerated Hyperfractionated Radiotherapy plus Concurrent Chemotherapy in Non-small Cell Lung Cancer
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摘要 [目的]观察局部晚期非小细胞肺癌常规放疗后予后程加速超分割放疗同步EP方案化疗的疗效及不良反应。[方法](1)单纯放疗组80例前2/3疗程常规设野放疗40Gy左右,后1/3疗程缩野改为后程加速超分割放疗。(2)协同化疗组54例在上述放疗的同时加用5个周期EP方案化疗。[结果]协同化疗组和单纯放疗组1年、2年、3年生存率分别为66.7%(36/54)、38.9%(21/54)、18.5%(10/54)和41.3%(33/80)、16.2%(13/80)、7.5%(6/80),2年生存率比较有显著性差异(χ2=8.73,P<0.01),有效率分别为88.9%和55.0%(χ2=16.849,P<0.01)。[结论]常规放疗后予后程加速超分割放疗协同化疗可以提高局部控制率和生存率。
机构地区 开平市中心医院
出处 《中国肿瘤》 CAS 2007年第7期564-565,共2页 China Cancer
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