摘要
目的 观察复方甘草甜素（美能）对慢性乙型肝炎的治疗作用.方法 将病人随机分为为两组,治疗组10例,用美能40ml/d.iv.3周后改为口服美能片75mg,每日三次.对照组10例,使用甘利欣150mg/d,VD.3周后改为口服甘利欣100mg,每日三次.结果 治疗组治疗后症状缓解率75%;血清ALT水平由（306.70±229.33）u/L降为（105.00±86.11）u/L;血清AST水平由（137.90±71.44）u/L降为（64.30±34.93）u/L;血清SB水平由（31.80±28.90）umol/L降为（16.20±3.43）umol/L.对照组治疗后症状缓解率为66.7%;血清ALT水平由（208.20±160.13）u/L降为（77.20±65.92）u/L;血清AST水平由（92.60±61.19）u/L降为（51.20±31.38）u/L;血清SB水平由（20.60±5.08）umol/L降为（11.70±2.06）umol/L.结论 复方甘草甜素（美能）的临床疗效与国内同类产品（甘利欣）相仿,具有较好的保肝、降酶作用,有一定的优势.
Objective To evaluate the treatment effect of Stronger Neo - Minophagen C （SNMC） on Chronic Hepatitis B （CHB）. Methotis Patients were randomly put into two groups. The treatment group has 10 cases, they took SNMC 40ml/d. iv. Three weeks later, they can take SNMC 75mg, three times a day. The control group has 10 patients, they took Diammonium Glycyrrhizinate （DGLL） 150mg/d, VD. Three weeks later, they can take DGLL 100mg, three times a day. Results In the treatment group, the symptoms of rate was 75% after treating; The serum levels of ALT decreased from （ 306.70 ± 229.33 ） u/L to （ 105.00 ± 86.11 ） u/L; The serum levels of AST decreased from （ 137.90 ±71. 44） u/L to （64.30 ±34.93 ） u/L; The serum levels of SB decreased from （31.80 ±28.90） umol/L to （ 16.20 ±3.43 ） umol/L. In the control group, the symptoms rate was 66.7 % after treating; The serum levels of ALT decreased from （ 208.20 ±160.13 ） u/L to （77.20 ± 65.92） u/L; The serum levels of AST decreased from （92.60 ±61.19） u/L to （51.20 ± 31.38 ） u/L; The serum levels of SB decreased from （20.60 ± 5.08 ） umol/L to （11.70 ±2.06）umol/L. Conclusion Compared with the same kind products in China, the clinical effective of SNMC is almost same. It plays an active role in the protective of the liver and the treatment ALT and AST.
