摘要
目的 探讨丹参酮ⅡA磺酸钠注射液对糖尿病肾病的辅助治疗作用.方法 将62例病人用随机数字表法随机分为治疗组和对照组各31例,在使用胰岛素的基础上合并丹参酮ⅡA磺酸钠注射液,观察测定血糖、血常规、血生化、肝功能、GFR、UAER血和尿β2-微球蛋白（β2-MG）的变化.结果 治疗前两组水平相近（t=0.010,P＞0.05）,治疗后明显低于治疗前;治疗前两组GFR相近,治疗后两组GFR均下降;治疗前两组UAER、血和尿β2-MG相近,治疗后两组UAER、血和尿β2-MG较前两组均下降,除尿β2-MG外,治疗组较对照组下降更为明显.结论 丹参酮ⅡA磺酸钠注射液明显改善GFR和UAER,且无明显副作用,因而在降糖治疗的基础上加用丹参酮ⅡA磺酸钠注射液将有助于早期糖尿病的治疗.
Objective Discussing the effects of sulfotanshinone sodium injection inoculation fluid to diabetes mellitus assistance treatment function. Method Divided 62 example patients into the treatment group and comparison group each 31 examples, merges the Sulfotanshinone sodium injection the observation determination blood sugar, blood , blood biochemistry, liver function, GFR, UAER blood and urine β2 -MG. Result Change before the result treatment two groups of levels are close （ t = 0.010, P 〉 0.05 ）, after the treatment obviously is lower than before the treatment; Before the treatment two group of GFR is close, treats latter two group of GFR to drop; Before the treatment two group of UAER, the blood and urine β2 - MG are close, treats latter two group of UAER, the blood and urine β2 - MG compares the first two groups to drop, besides urine β2 - MG, the treatment group comparatively compares the group to drop obviously. Conclusion Sulfotanshinone sodium injection obviously improves GFR and UAER, also not obvious side effect, thus in will fall the sugar treatment in the foundation to add with Sulfotanshinone sodium injection is helpful to the early diabetes treatment.
关键词
糖尿病肾病
丹参酮ⅡA磺酸钠
生化指标
Diabetes mellitus Sulfotanshinone sodium injection Biochemistry target
