摘要
目的 观察硫普罗宁治疗酒精性肝病的疗效.方法 60例酒精性肝病患者随机分为两组,治疗组(A组)30例给予硫普罗宁注射液;对照组(B组)30例给予常规护肝(肝泰乐、维生素C)治疗.疗程均为4周.结果 治疗组总有效率96.7%,与对照组相比有显著差异(P<0.01);治疗组ALT、AST、r-GT复常率分别96.7%、93.3%、90%,与对照组相比有显著差异(P<0.01);治疗组ALT、AST、r-GT下降幅度均明显高于对照组(P<0.01).结论 硫普罗宁治疗酒精性肝病疗效较好,优于肝泰乐、维生素C.
Objective Tiopronin treatment of alcoholic liver disease. Methods 60 patients with alcoholic liver disease were randomly divided into two groups, the treatment group (group A) 30 cases given Tiopronin injection; control group (group B) received conventional Hugan 30 cases (Glucurolocatone, vitamin C) treatment. Treated for 4 weeks. Results Showed that the total efficiency was 96.7%, a significant difference compared with control group (P 〈0.01 ) ; treatment ALT, AST, the recovery rate of 96.7% r -GT, 93.3% ,90%. significant differences compared with the control group ( P 〈 0.01 ) ; treatment ALT, AST, r - GT decreased significantly (P 〈 0.01 ). Condusion Tiopronin treatment of alcoholic liver disease better than Glucurolocatone, vitamin C.
关键词
硫普罗宁
酒精性肝病
肝泰乐
维生素C
Tipronini Alcoholic liver disease Glucurolocatone Vitamin C