摘要
目的探讨99mTc-Octreotide生长抑素受体显像诊断肺癌的价值。方法43例肺部肿瘤病人,静脉注射99mTc-Octreotide 15 min、1 h3、h后行前后位平面显像,2～3 h行SPECT/CT同机断层融合显像。勾画感兴趣区,分别测定肿瘤和对侧正常肺组织的放射性比值(T/N),并将影像最终诊断结果与病理检查结果进行对比分析。结果99mTc-Octreotide显像诊断肺癌的灵敏度、特异度和准确度分别为94.4%、85.7%和93.0%。小细胞肺癌(SCLC)的T/N值高于非小细胞肺癌(NSCLC),差异有显著性(t=6.469,P<0.01)。结论99mTc-OctreotideSPECT/CT同机断层融合显像对肺癌具有较高的诊断价值。
Objective To evaluate the value of ^99mTc-octreotide somatostatin receptor scintigraphy in the diagnosis of lung neoplasm. Methods Patients with pulmonary neoplasm （n=43） were studied with ^99mTc-Octreotide scintigraphy. Planar imaging was obtained after injection of ^99mTc-octreotide at 15 min, 1 h,and 3 h, SPECT/ CT fusion images were taken at 2-3 h after injection. All scintigraphically detected lesions were confirmed histopathologically. Ratios of tumor to normal tissue （T/N） were calculated. Results Sensitivity, specificity and accuracy of ^99mTc-octreotide in detection of lung cancer were 94. 4%, 85.7% and 93.0%, respectively. The T/N ratio in small cell lung cancer was significantly higher than that in non-small cell one （t=5. 469,P〈0.01）. Conclusion ^99mTc-octreotide SPECT/ CT fusion imaging is a good method to detect the primary lung cancer.
出处
《青岛大学医学院学报》
CAS
2007年第4期311-312,315,共3页
Acta Academiae Medicinae Qingdao Universitatis
关键词
肺肿瘤
锝
放射性核素显像
受体
生长抑素
诊断
lung neoplasms
technetium
radionuclide imaging
receptors, somatostatin
diagnosis
