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口服RU_(486)配伍阴道给米索终止早孕

Termination of Early Pregnancy by Oral Mifepristone in Combination with Misoprostol Administered by the Vaginal Route
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摘要 对要求药物流产的妇女随机分成两组,并从中各随机抽100名分别予以顿服米非司酮(RU486)150mg后48h,经阴道给米索600μg(实验组)及RU486序贯给药72h后口服米索600μg(对照组)。结果两组完全流产率、不全流产率、失败率、阴道流血时间、月经恢复时间均无显著性差异(P>0.05),仅胃肠道副反应实验组明显低于对照组(P<0.01),具显著性差异。 Of 200 consecutive women who reviped edrly induced abortion, 100 women chose oral RU 486 (mifepristone) 150 mg and misoprostol 600 μg, the others using a new regimen of oral RU 486 150 mg and Vaginal misoprostol 600 μg The complete abortion rate was 95 0% in oral misoprostol group and it was 97 0% in vaginal misoprostol group (P>0 05) The imcomplete abortion rate was 4 0% in oral misoprostol group and it was 3 0% in vaginal misoprostol group (P>0 05) The gastrointestinal side effects rate was 47 0% in oral misoprostol group and it was 24 0% in vaginal misoprostol group (P<0 01) The main side effects were gastrointestinal, but usually mild and didn’t necessitate any treatment Oral RU 486 in combination with misoprostol administered by the vaginal route be used to induce abortion is highly effective, has a low incidence of side effects and appear to be highly acceptable to women
出处 《贵阳医学院学报》 CAS 1997年第1期45-46,65,共3页 Journal of Guiyang Medical College
关键词 米非司酮 米索前列腺 药物流产 终止妊娠 mifeprstone misoprostol medical induction of abortion
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