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低钾型周期性麻痹158例临床分析 被引量:3

Clinical Analysis of 158 Patients with Hypokalemic Periodic Paralysis
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摘要 目的:分析低血钾型周期性麻痹(Hypo PP)的临床特点。方法:对2000年1月~2007年1月本科接诊的158例Hypo PP患者的临床资料进行回顾分析。结果:(1)原发性115例,继发性43例,其中甲亢41例。(2)Hypo PP最早表现为四肢弛缓性的肌无力,重症患者可出现呼吸肌麻痹及心率失常。(3)血钾越低患者临床症状及其他辅助检查变化越重,疗效越差;肌酶升高在一定程度上反映肌肉损害情况。结论:Hypo PP以肌无力或麻痹伴低钾血症为其临床特点,及早诊治是关键;对重度HypoPP进行心电监护、补钾、抗心律失常、抗休克治疗和呼吸机辅助呼吸是抢救成功的重要措施;对继发性HypoPP患者应强调病因治疗。 Objective: To investigate the clinical features of Hypokalemic periodic paralysis(HypoPP). Method: The clinical data of 158 patients with HypoPP were retrospectively studied and summarized. Results: (1)idiopathic 115 eases, secondary 43 eases. 41 were secondary from hyperthyroidism. (2)The classical appearance was sluggish myoasthenia of four limbs and hypokalemia,and some serious HypoPP experienced respiratoryparalysis and arrhythmia. (3) The lower was the serum kalemia level, the severer of the clinical symptoms and the worse was the cure effect. The rise of the serum ereatinase may reflect the damage level of skeletal muscle. Conclusion: HypoPP is a disorder characterized by flaccid paralysis accompanied by lowered serum potassium levels. To diagnose and treat as early as possible is the key point. Eleetroeardio-monitoring, antiarrhythraie drug, eountershoek treatment and ventilatory support are important measures for serious eases. Etilogieal treatment should be underlined for secondary eases.
出处 《岭南急诊医学杂志》 2007年第3期189-190,共2页 Lingnan Journal of Emergency Medicine
关键词 低钾血症 周期性麻痹 kaliopenia periodic paralysis
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