摘要
目的 调查重症监护病房（ICU）应用人工气道进行机械通气的食管癌患者伴呼吸机相关性肺炎（VAP）的致病菌群及探讨治疗对策。方法 对23例建立人工气道的机械通气伴VAP的食管癌患者痰培养分离出的54株致病菌进行分析。结果革兰阳性菌占18．52％。革兰阴性菌占74．07％，分别列前2位的是铜绿假单胞菌（29．63％）、不动杆菌属（25．93％）。所有革兰阴性菌对抗菌药物的耐药率呈上升趋势，革兰阳性菌以耐药金葡菌为主（40％）。结论 食管癌患者术后VAP的致病菌多为耐药菌，为避免耐药率的升高，临床需要合理使用抗生素并给予患者综合治疗。
Objective To investigate the distribution and sensitivity of pathogenic bacteria in ventilator associated pneumonia （VAP） in the patients after surgical treatment for esophageal carcinoma and to explore the therapy. Methods In 23 patients, 54 strains of pathogens in VAP were classified and drug resistance was analyzed. Results Ten（18.52%） of 54 strains were gram positive bacilli,40 （74.07%） of 54 strains were gram negative bacilli. The predominant pathogens were pseudomonas aeruginosa （29.63%）, acinetobacter baumanii （25.93%）. Drug sensitivity test showed that the drug resistance rate was in an increasing tendency in pathogens. Among the gram positive bacteria, durg-resistant stapthylococcus aureus was the most common（40%）. Conclusions The main pathogens are drug-resistant in VAP after surgical treatment for esophageal carcinoma. In order to control the drug resistance, reasonable application of antibiotics should be emphasized and patients should be treated synthetically.
出处
《国际呼吸杂志》
2007年第12期895-897,共3页
International Journal of Respiration
关键词
食管癌
呼吸机相关性肺炎
机械通气
Esophageal carcinoma
Ventilator associated pneumonia Mechanical ventilation
