摘要
目的：本文旨在探讨中华麦饭石防治大鼠肝炎、肝硬化和肝癌时微量元素的作用方法：给ｗｉｓｔａｒ大鼠食用二甲基奶油黄饲料，同时饮用１０％中华麦饭石浸液共２６周。用ＩＣＰ法检测肝炎、肝硬化和肝癌大鼠全血１０种微量元素。结果：肝炎时实验组仅Ｍｎ显著高于对照组（Ｐ＜００５）。肝硬化时实验组Ｍｎ、Ｓｉ、Ｂａ、Ｆｅ、Ｚｎ和Ｓｅ均显著高于对照组，Ｃｕ显著低于对照组（Ｐ＜００５～０．００１）。肝癌时实验组Ｍｎ、Ｓｉ、Ｂａ、Ｆｅ、Ｚｎ、Ｓｅ和Ｍｏ继续高于对照组，Ｃｕ和Ｃｒ低于对照组（Ｐ＜０００１）。除Ｓｉ外，实验组和正常对照组微量元素差异无显著意义（Ｐ＜００５）。结论：１肝病越重，微量元素变化越明显。２中华麦饭石能维持机体微量元素的正常状态，对大鼠肝炎、肝硬化和肝癌防治具有重要作用。
Aims:To find out the effect of microelement on DAB-induced hepatitis and cirrhosis and hepatocarcinoma prevented by China medical stone (CMS) in rats.Methods:177 male wistar rats were in experiment,rats were fed with DAB-Food and 10% China medical stone soak for 26 weeks.Ten kinds of microelements were detected with ICP method in rats with hepatitis and cirrhosis and hepatocarcinoma respectively.Results:Amounts of Mn and Si were significantly higher in experimental group than controls in the rats with hepatitis (P<0 05) Amounts of Mn,Si,Ba,Fe,Zn and Se were significantly higher and amount of Cu was lower in experimental group than controls (P<0.05-0.001) in the rats with cirrhosis.Amounts of Mn,Si,Ba,Fe,Zn,Se and Mo were contineously higher and amounts of Cu and Cr were contineously lower in experimental group than controls (P<0.001) in the rats with hepatocarcinoma.Amounts of microelements were not signficantly different except Si between experimental group and normals.Conclusions:1.the more serious hepatic disese the more obvious a change of the microelement .2.CMS could maintain a normal condition of the microelement in body and play an important role in preventing hepatitis and cirrhosis and hepatocarcinoma.
出处
《胃肠病学和肝病学杂志》
CAS
1997年第1期74-77,共4页
Chinese Journal of Gastroenterology and Hepatology
关键词
麦饭石
肝炎
微量元素
肝硬变
肝肿瘤
China medical stone Hepatitis Cirrhosis Hepatocarcinoma Microelement Rat
