摘要
Objective To analyze differences in proliferative, apoptotic and metastatic activities between stage Ⅰ peripheral BAC and adenocarcinoma of the lung. Methods Flow cytometry and immunohistochemistry examinations of paraffin-embedded specimens were performed in 15 patients with BAC and 19 patients with adenocarcinoma of the lung. Determination of the S-phase fraction, proliferative index,DNA index and proportion of apoptotic cells to assess cancer cell metastatic activity. Results The results of flow cytometry revealed no difference in distribution among the S-phase fraction, proliferative index, DNA index,but proportion of apoptotic cells in BAC was higher than that in adenocarcinoma.
