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干扰素与阿地福韦序贯治疗慢性乙型肝炎疗效分析

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摘要 目的:分析干扰素与阿地福韦序贯治疗慢性乙型肝炎疗效。方法:40例乙型肝炎患者随机分成2组-序贯治疗组和单用组。序贯组应用a-2b干扰素500万单位,隔日1次,肌内注射。30 d后换用阿地福韦,10 mg,1 d1次,口服。连用5 mon。单用组应用阿地福韦,10 mg,1 d 1次,口服,疗程6 mon。观察干扰素和阿地福韦的不同用药方式对患者血清学指标及病毒标志物的影响。结果:干扰素、阿地福韦序贯治疗与单用阿地福韦的疗效比较有显著差异,序贯组疗效优于单用组。结论:干扰素和阿地福韦序贯治疗可用于治疗慢性乙型肝炎的首选治疗。
作者 周永安
出处 《河南大学学报(医学版)》 CAS 2007年第2期35-36,共2页 Journal of Henan University:Medical Science
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