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额颞叶变性的研究进展 被引量：3

Fronotemporal lobar degeneration: an update
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摘要 额颞叶变性(frontotemporal lobar degeneration,FTLD)是以局限性额叶/颞叶变性为特征的非阿尔茨海默病(Alzheimer disease,AD)痴呆综合征。近年的研究发现它与tau蛋白的变性有关,并与皮质基底节变性(corticobasal ganglionic degeneration,CBD)、进行性核上性麻痹(progressive supranuclear palsy,PSP)、运动神经元病(motor neuron disease,MND)相关或重叠。本文就FTLD的病因、病理、遗传学、临床分型以及诊断标准等方面的研究进展作一综述。 Frontotemporal lobar degeneration （FTLD） is a non-Alzheimer dementia syndrome characterized by focal atrophy of the frontal and/or temporal lobes. Recently, it has been found that FTLD is related to the degeneration of tau protein, and is closely associated with corticobasal ganglionic degeneration, progressive supranuclear palsy, and motor neuron disease. This article reviews the progress in etiology, genetics, pathology, clinical features, and diagnostic criteria of FTLD.
作者 吴建新 陈先文
机构地区 解放军第 安徽医科大学第一附属医院神经内科
出处 《第二军医大学学报》 CAS CSCD 北大核心 2007年第2期204-208,共5页 Academic Journal of Second Military Medical University
关键词 额颞叶变性 TAU蛋白 病因 病理学 诊断 frontotemporal lobar degeneration tau protein etiology pathology diagnosis
分类号 R749.1 [医药卫生—神经病学与精神病学]
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参考文献41

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同被引文献28

  • 1张玉梅,王拥军,韩在柱,舒华.原发性进行性失语1例报道[J].中华物理医学与康复杂志,2005,27(6):367-369. 被引量：5
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引证文献3

二级引证文献7

第二军医大学学报
2007年 第2期

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