摘要
目的:研究冠心生脉颗粒抗心肌缺血缺氧的药理作用。方法:观察在体心外膜心电图ST段抬高总数及其ST段抬高的总点数变化,采用定量组织学N-BT染色法,用落点求积法和重量求积法,以求得梗死面积和梗死重量的百分率。结果:冠心生脉颗粒能明显减少犬因心肌缺血而引起的ST段抬高及其ST段抬高的总点数,有效降低心肌缺血后梗死面积和梗死区的百分率。结论:冠心生脉颗粒具有明显增加缺血区心肌供血供氧,减轻心肌梗死程度,缩小心肌梗死范围,对冠心病有良好的防治作用。
Objective： To observe the pharmacological effect of Guanxinshengrnai granule on anti-myocardial ischemia and anoxic. Methods：To observe the sum of the raised ST segment and raised ST segment dot number in vivo epicardium electrocardiogram, adoptingthe method of ration histology N-BT dyeing, using fall point planimetry and weight planimetry to calculate the infarct size and percentage of infarct weight. Resuhs：Guanxinshengmai granule can reduce the dog＇s raised ST segment and raised ST .segment dot number obviously, and reduce the area of infarct and the percentage of the section of infarct efficiency. Conclusion：Guanxinshengmai granule can increase the oxygen supply of ischemic myocardium area, alleviate the degree of myocardial infarct, reduce the area of myocardial infarct, it has better effect on prevention an cure the coronary heart disease.
出处
《江西中医学院学报》
2007年第3期70-72,共3页
Journal of Jiangxi College of Traditional Chinese Medicine
关键词
冠心生脉颗粒
心肌缺血
在体心外膜心电图
心肌梗死
犬
Guanxinshengmai granule
Myocardial Ischemia
Epicardium electrocardiogram in vivo
Myocardial infarct
Dog
