摘要
目的恶性胶质瘤是预后极差的常见颅内恶性肿瘤,本研究报告恶性胶质瘤外照射加X刀推量的治疗模式的疗效。方法对15例确诊为恶性胶质瘤的患者进行了外照射加X刀推量的治疗。外照射50 Gy/25 F/5W后,紧接着用X刀推量7～10Gy。结果治疗后近期效果满意,无严重神经功能障碍并发症。3例患者分别死于X刀后4、5、11月,余均健在。全组仅1例在治疗后3月出现脑水肿,给予对症治疗后缓解。余患者无严重的放射反应。结论恶性胶质瘤外照射加X刀推量的治疗模式是可行的,疗效较好。
Objective Malignant glioma is the most common primary malignant brain tumor with extremely poor prognosis, We investigated the effects of stereotactic radiosurgery （SRS） in addition with the conventional external beam radiation therapy （EBRT） on patients with malignant glioma. Methods A total of 15 patients diagnosed as malignant glioma were treated with SRS followed by EBRT （50 Gy/25 F/5 W）, dose ofradiosurgery ranging from 7 to 10 Gy. Results Short-term effects after the treatment were satisfactory, no complications of severe neurological deficits. Three patients died respectively in the 4th, 5th and 1 lth month after X-knife treatment; the rest are alive. Cerebral edema occurred only to one case in the 3rd month after X-knife treatment, but the patient＇s symptoms were relieved after symptomatic treatment; the other patients had no severe radiation reaction, Conclusion The combined treatment of SRS in addition with the conventional EBRT is feasible and applicable for the treatment of malignant glioma.
出处
《中华神经医学杂志》
CAS
CSCD
2007年第6期621-623,共3页
Chinese Journal of Neuromedicine
关键词
神经胶质瘤
外照射
立体定向放射外科
Malignant glioma
External beam radiation therapy
Stereotactic radiosurgery
