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阿托伐他汀治疗不稳定型心绞痛临床观察 被引量:1

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摘要 目的观察阿托伐他汀对不稳定型心绞痛(UAP)患者血清高敏C-反应蛋白(hs-CRP)、基质金属蛋白酶-9(MMP-9),内皮素-1(ET-1)、总胆固醇(TC)、甘油三脂(TG)的影响。方法将85例住院治疗的UAP患者分为常规治疗组(37例)和常规加阿托伐他汀治疗组(48例),给予阿托伐他汀20 mg/d共14 d,治疗前后测定两组TC、TG、hs-CRP、MMP-9、ET-1水平并进行比较。结果治疗组治疗后TC、TG、hs-CRP、MMP-9、ET-1水平低于对照组,差异有统计学意义(P<0.05)。结论短期应用阿托伐他汀治疗UAP可以抑制炎症反应,改善内皮功能,稳定动脉粥样硬化斑块,减少冠脉事件发生。
出处 《右江医学》 2007年第3期250-251,共2页 Chinese Youjiang Medical Journal
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参考文献10

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