摘要
目的探讨糖化血红蛋白Alc(HbAlc)及糖化血清蛋白(GSP)的检测对2型糖尿病(DM)监控的临床意义。方法选择167例临床确诊的2型DM患者和120例健康体检者,进行空腹血糖(FPG)、餐后2h血糖(2hPG)、HbAlc、GSP指标的检测,结果进行统计学处理。结果2型DM组FPG、2hPG、HbAlc及GSP等指标与健康对照组比较差异有统计学意义(P<0.01),DM患者的HbA1c与FPG、2hPG呈显著正相关。经过治疗后,病情得到控制的DM组FPG、2hPG、HbAlc及GSP等4项指标与健康对照组比较差异无统计学意义(P>0.05),但HbAlc水平与FPG、2hPG水平并不完全一致。结论FPG、2hPG、HbAlc及GSP的联合检测有助于2型DM的早期诊断,对控制DM并发症的发生、发展及DM的预后监测均有重要临床意义。
Objective To investigate the clinical significance of HbAlc and glycated serum protein （GSP） determination in monitoring type 2 diabetes mellitus. Methods 167 cases of patients with type 2 diabetes mellitus in our hospital and 120 healthy people were enrolled. Fasting plasma glucose （FPG）, 2hPG, HbAlc and GSP were examined. Then the results were compared and analyzed statistically. Results Compared with those of healthy control group, FPG, 2hPG, HbAlc and GSP in type 2 diabetes mellitus group increased significantly （P〈0.01）. HbAlc was positive correlative to FPG and 2hPG in type 2 diabetes mellitus group. After treatment, there wasn＇t significant difference of FPG, 2hPG, HbAlc and GSP between the two groups （P〉0.05）, but HbAlc alternating level wasn＇t consistent to that of FPG and 2hPG. Conclusion To examine FPG, 2hPG, HbAlc and GSP at the same while is helpful for diagnosis of type 2 diabetes mellitus, control of complications and prognosis monitoring.
出处
《检验医学与临床》
CAS
2007年第6期483-484,共2页
Laboratory Medicine and Clinic
