摘要
目的:评价可塞风与曲马多自控静脉镇痛的镇痛效果及不良反应。方法:40例ASAⅠ-Ⅱ级喉癌根治术患者,随机分为L(可塞风)组和T(曲马多)组,手术缝合时,L组静注可塞风8mg,T组静注曲马多100mg,手术结束前5分钟经外周静脉连接自控式镇痛泵。输注模式:背景量2ml/h,追加量0.5ml,锁定时间15min。药液配制:L组:可塞风48mg加生理盐水至120ml;T组:曲马多1000mg加生理盐水至120ml。镇痛期间观察视觉模拟评分(VAS)、舒适评分(BCS)及不良反应。结果:两组比较VAS与BCS均无统计学差异。曲马多组恶心、呕吐、出汗等反应高于可塞风。结论:可塞风与曲马多都能提供良好的术后镇痛。可塞风伴有较少的不良反应,在临床上更值得应用和推广。
Objective： To evaluate the efficacy of xafon and tramadol on patient-controlled intravenous analgesia （PCIA） in patients underwent larynx cancer operations. Methods： 40 patients （ASA I- Ⅱ） larynx cancer operations under general anesthesia were randomly allocated to either group L or gruop T with 20 cases each.At the time of wound closure,xafon was administered intravenously at a dose kf 8mg（group L）, tramadol was administered intravenously at a dose of 100 mg （group T）. The analgesic prescription included xafon 48rag diluted with Ns to 120ml（group L）,tramadol 1000rag diluted with Ns to 120ml（group T）,and continuous infused at a rate of 2ml/h, bolus dose was 0.5ml and lock-out interval 15rain. To observe the visual analgesia score （VAS）, Bruggrmann comfort score（BCS） and adverse events during the analgesia. Results： There was no statistical difference in VAS and BCS （P〉0.05）. Group T was higher than group L in nausea, vomitus and diaphoresis,et al. Conclusion： Group L can provide the same analgesic efficacy as group T. Postoperative analgesia with xafon is more worthy of application in clinic associated with a lower incidence of adverse events.
出处
《中国伤残医学》
2007年第3期27-28,共2页
Chinese Journal of Trauma and Disability Medicine
关键词
可塞风
曲马多
喉癌
镇痛
Xafon
Tramadol
Larynx cancer
Analgesia
