摘要
OBJECTIVE To summarize the clinical characteristics, pathology, treatment and prognosis of malignant lymphoma of the prostate. METHODS Clinical data from 29 patients with primary malignant lymphoma of the prostate were reviewed retrospectively. The median age was 66 years. Clinical signs and symptoms were due to lower urinary tract obstruction resulting from a diffusely enlarged prostate. Prostate biopsies revealed diffuse large B-cell non-Hodgkin＇s lymphoma. The therapeutic modalities included prostatectomy, radiotherapy and chemotherapy. RESULTS Extraprostatic involvement at various sites became evident in 19 of the 29 patients after diagnosis. Ten patients died from lymphoma with a median survival of 23 months （range, 2-30 months）. Seven patients were alive up to 60 months. CONCLUSION Malignant lymphoma involving the prostate was rare and has a rather poor prognosis. Prognosis related to the patient age, histologic type, and treatment or clinical stage of the disease at presentation.
OBJECTIVE To summarize the clinical characteristics,pathology,treat- ment and prognosis of malignant lymphoma of the prostate. METHODS Clinical data from 29 patients with primary malignant lympho- ma of the prostate were reviewed retrospectively.The median age was 66 years.Clinical signs and symptoms were due to lower urinary tract obstruc- tion resulting from a diffusely enlarged prostate.Prostate biopsies revealed diffuse large B-cel non-Hodgkin's lymphoma.The therapeutic modalities included prostatectomy,radiotherapy and chemotherapy. RESULTS Extraprostatic involvement at various sites became evident in 19 of the 29 patients after diagnosis.Ten patients died from lymphoma with a median survival of 23 months(range,2-30 months).Seven patients were alive up to 60 months. CONCLUSION Malignant lymphoma involving the prostate was rare and has a rather poor prognosis.Prognosis related to the patient age,histo- logic type,and treatment or clinical stage of the disease at presentation.
