摘要
本实验在中医温病学理论指导下,采用肺炎双球菌作造模因素,初步建立了家兔邪热壅肺证动物模型。首先,观察了模型动物邪热壅肺证的症、征、体温动态变化,白细胞、中性粒细胞,全血粘度,血浆粘度、血清钾、钠、血细菌培养及有关病理形态学变化。其次,用麻杏石甘汤进行了实验性治疗,观察了用药后的效应,实验室检查指标的变化及死亡数。实验结果,模型动物出现发热,气喘、鼻煽等症状,基本符合温病邪热壅肺证的辨证要点,而一些生理,坐化变化可作为邪热壅肺证辨证的参考指标。 再次,对麻杏石甘汤治疗邪热壅肺证的效应作了初步分析,其结果在诸方面都优于模型组。
The rabbit 'Xie Re Yong Fei Syndrome' (XRYFS) animal model was primary reproduced under the direction of theory of TCM wenbing, which adopted pneumococci. First) What were observed in model animal XRYFS were symptom, sign, mobile variations of temperature,leukocyte, neutrophilic leukocyte whole blood viscosity, plasma viscosity, potassium in serum, sodium in serum, bacterial cultivation and pathologic change of morphology.Se-cond, experimental treated with Ma Xing Shi Gan. Decoction ( MX S G D ) . Observed the treatment effect, varieties of laboratory examination indexes and fatalities, i.e,The results showed that the symptoms such as fever, breathlessness, alanasi flap and so on in modeel pattern basic fit into dia-lesctical main point of Wenbing XRYFS, Some fluctuations of physiologyic and biochemical can be regarded as dialectical reference index of XRYFS,
Third, primary analysised the effect of treatment of MXSGD, It was found that the treating group is better than the model one.
出处
《甘肃中医学院学报》
1990年第1期47-51,共5页
Journal of Gansu College of Traditional Chinese Medicine