摘要
苯乙酸乙酯与碳酸二乙酯进行Claisen酯缩合后,不经加热脱羧,直接得苯丙二酸二乙酯而制备苯巴比妥,实现了苯巴比妥合成工艺的绿色化。
Ethyl phenylacetate and diethyl forminate carried on Claisen condensation to be transformed into diethyl phenylmalonate without calefaction and decarboxylation for Phenobarbital preparation. Achieve Environmentally Friendly Synthetic method of Phenobarbital.
出处
《甘肃高师学报》
2007年第2期37-38,共2页
Journal of Gansu Normal Colleges
基金
甘肃省教育厅基金资助项目(0210-05)
关键词
苯巴比妥
苯乙酸乙酯
碳酸二乙酯
绿色合成
Phenobarbital
Ethyl phenylacetate
diethyl forminate
Environmentally Friendly Synthesis
