摘要
目的:比较阻塞性睡眠呼吸暂停低通气综合征(OSAHS)若干临床指标的诊断价值,寻找简易可行的诊断方法。方法:对352例经整夜多导睡眠图确诊的OSAHS患者和67例鼾症患者详细询问病史,行主客观评分及身体参数测量。用前进法Logistic回归分析筛选出最具有诊断价值的指标,作多变量的ROC曲线分析,并和用单一指标简易诊断OSAHS的方法比较。结果:ESS评分,颈围,最低氧饱和度,糖尿病史具有较好的诊断预测价值,四项指标的联合比单一指标具有更好的诊断性,灵敏度约为76%,特异度约为96%,ROC曲线下面积为0.926,最大Youden指数为0.714。结论:多指标联合诊断OSAHS好于用单一指标,可以用于临床简易诊断和筛查。
Objective：To compare the diagnostic value of some clinical parameters of patients with obstructive sleep apnea-hypopnea syndrome （OSAHS）, and look for a simple way to diagnose this disease. Methods： The case history, clinical scale, Epworth sleeping scale（ESS） and body parameters of the OSAHS patients diagnosed by PSG and snoring disease patients were recorded respectively. Multi-variable ROC curve would be used to screen the most valuable clinical parameters which were used with forward conditional Logistic regression analysis. Results： ESS, neck circumference, min SpO2, and history of diabetes mellitus had good predictive value for diagnosis. Combination of the four parameters and useing the Logistic regression equation model were a good and new diagnostic method. Sensitivity is 76%, spesificity 96%, maximum Youden index 0.714, and area under ROC curve 0.926. Conclusion： Combination of multi-parameters is better than single one in OSAHS diagnosis, and can be used in simple clinical diagnosis.
出处
《温州医学院学报》
CAS
2007年第3期250-252,255,共4页
Journal of Wenzhou Medical College
