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急性髓系白血病诱导缓解治疗期残留白血病细胞比例的预后价值 被引量:3

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摘要 染色体核型异常及其受累基因是急性髓系白血病(AML)最重要的独立预后因素和治疗策略制定的依据,但由于细胞和分子遗传学检测技术要求高,目前在我国尚难以成为常规。已有研究表明通过白血病细胞的清除速度及程度评估急性白血病的早期疗效具有重要的临床意义。我们对原发初治AML患者在诱导缓解治疗期不同时点残留白血病细胞比例的预后意义进行了探讨,报道如下。
机构地区 中国医学科学院
出处 《中华血液学杂志》 CAS CSCD 北大核心 2007年第5期341-343,共3页 Chinese Journal of Hematology
基金 新世纪优秀人才支持计划基金资助项目(NCET-05-0173)
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  • 1Wheatley K, Burnett AK, Goldstone AH, et al. A simple, robust, validated and highly predictive index for the determination of risk-directed therapy in acute myeloid leukaemia derived from the MRC AML 10 trial. United Kingdom Medical Research Council' s Adult and Childhood Leukaemia Working Parties. Br J Haematol, 1999,107:69- 79.
  • 2Slovak ML, Kopecky KJ, Cassileth PA, et al. Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: a Southwest Oncology Group/Eastern Cooperative Oncology Group Study. Blood, 2000,96:4075-4083.
  • 3Byrd JC, Mrozek K, Dodge RK, et al. Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia : results from Cancer and Leukemia Group B ( CALGB 8461 ). Blood, 2002,100:4325-4336.
  • 4Hiddemann W, Clarkson BD, Buchner T, et al. Bone marrow cell count per cubic millimeter bone marrow : a new parameter for quantitating therapy-induced cytoreduction in acute leukemia. Blood, 1982, 59: 216-225.
  • 5Panzer-Grumayer ER, Schneider M, Panzer S,et al. Rapid molecular response during early induction chemotherapy predicts a good outcome in childhood acute lymphoblastic leukemia. Blood, 2000, 95:790- 794.
  • 6Sandlund JT, Harrison PL, Rivera G, et al. Persistence of lymphoblasts in bone marrow on day 15 and days 22 to 25 of remission induction predicts a dismal treatment outcome in children with acute lymphoblastic leukemia. Blood, 2002, 100:43-47.
  • 7肖志坚,郝玉书.急性白血病诱导缓解治疗期间残留白血病检测的重要意义[J].中华血液学杂志,2003,24(1):5-5. 被引量:10
  • 8Buchner T, Hiddemann W, Wormann B, et al. Double induction strategy for acute myeloid leukemia: the effect of high-dose cytarabine with mitoxantrone instead of standard-dose cytarabine with daunorubicin and 6-thioguanine: a randomized trial by the German AML Cooperative Group. Blood, 1999, 93:4116-4124.
  • 9Kern W, Haferlach T, Schoch C, et al. Early blast clearance by remission induction therapy is a major independent prognostic factor for both achievement of complete remission and long-term outcome in acute myeloid leukemia: data from the German AML Cooperative Group (AMLCG) 1992 Trial. Blood, 2003, 101:64-70.
  • 10Haferlach T, Kern W, Schoch C, et al. A new prognostic score for patients with acute myeloid leukemia based on cytogenetics and early blast clearance in trials of the German AML Cooperative Group. Haematologica, 2004,89:408-418.

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