摘要
目的总结氯仿中毒患者的临床表现及诊断方法。方法回顾性分析1996～2006年收治的36例氯仿中毒患者的临床表现、实验室检查、诊断及中毒机制。结果36例患者氯仿接触史明确,临床表现复杂多样,其中肝功能受损占80.6%、中枢神经损害占60.8%、皮肤损伤占42.3%,其他系统器官也有不同程度受损表现,且与前三者合并存在。在实验室检查中83%的患者前清蛋白(PA)降低,70%ALT升高。结论临床诊断必须有明确的氯仿接触史、临床表现和可靠的实验室检查指标,且需排除其他疾病。氯仿中毒可致多个器官损害,临床表现可分为肝型、脑型、皮肤型和混合型,以肝型最多见,实验室检查中以PA较敏感。
Objective To summarize the clinical manifestations and diagnostic methods of patients with chloroform poisoning. Methods Data of 36 patients with chloroform poisoning hospitalized from1996 to 2006 was analyzed retrospectively, In terms of their clinical manifestations, laboratory examination, diagnosis and toxic mechanism. Results The patients with chloroform poisoning had their specific histories of chloroform contacts, and their clinical manifestations were complicated and diversified. There were 80. 6% of them with livers damaged, 60. 8% of them with center nerve systems injured, 42. 3% of them with skin impaired. Other organs were also harmed simultaneously with the aforementioned organs or tissues in different degrees. Laboratory examination indicates： 83% of the patients＇ prealbumin （PA） level was decreased, and 70% of the patients＇ ALT level was increased. Conclusion Clinical diagnosis must be provided with the specific histories of contacting chloroform, clinical manifestations and credible assistant check - ups, and must exclude other diseases. Chloroform poisoning could injure many human body＇s systems or organs, and they can be divided into liver -type, cerebral type, skin -type and mixed type. The liver - type is the commonest one, and the test of PA level is the most sensitive in laboratory examination.
出处
《中国全科医学》
CAS
CSCD
2007年第10期823-824,共2页
Chinese General Practice
关键词
氯仿
中毒
病理状态
体征和症状
诊断
Chloroform
Poisoning
Pathological Conditions, Signs and Symptoms
Oiagnosis
