摘要
黄芩甙元及其苄基衍生物的制备与抗人免疫缺陷病毒实验研究赵晶张致平陈鸿珊陈湘红张兴权（中国医学科学院、协和医科大学医药生物技术研究所，北京１０００５０）黄芩（ＳｃｕｔｅｌａｒｉａｂａｉｃａｌｅｎｓｉｓＧｅｏｒｇｉ）有广泛的生物活性。黄芩提取物及其...
Baicalein (1) was prepared from baicalin by acid hydrolysis with yield of 24%. 5,6 Dibenzyl 7 hydroxyl flanone (4) and 6 benzyl 5,7 dihydroxyl flanone (5) were obtained by using different benzylating agents, and then hydrolyzing those benzylated compounds. The total yield of (4) and (5) were 5 9% and 5%, respectively. Both 4 and 5 were less effective than baicalien on inhibition of HIV 1 RT in vitro .
出处
《药学学报》
CAS
CSCD
北大核心
1997年第2期140-143,共4页
Acta Pharmaceutica Sinica
基金
国家自然科学基金
