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Bioactivity of bioresorbable composite based on bioactive glass and poly-L-lactide 被引量：5

Bioactivity of bioresorbable composite based on bioactive glass and poly-L-lactide
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摘要 Bioactive and bioresorbable composite was fabricated by a solvent evaporation technique using poly-L-lactide(PLLA) and bioactive glass (average particle size: 6.8 μm). Bioactive glass granules are homogeneously distributed in the composite with microcrack structure. The formation of hydroxyapatite(HA) on the composite in simulated body fluid(SBF) was analyzed by scanning electron microscopy(SEM), energy dispersive spectroscopy(EDS), X-ray diffraction(XRD), and Raman spectra. Rod-like HA crystals deposit on the surface of PLLA/bioactive glass composite after soaking for 3 d. Both rod-like crystals and HA layer form on the surface for 14 d in SBF. The high bioactivity of PLLA/bioactive glass composite indicates the potential of materials for integration with bone. Bioactive and bioresorbable composite was fabricated by a solvent evaporation technique using poly-L-lactide（PLLA） and bioactive glass （average particle size： 6.8μm）. Bioactive glass granules are homogeneously distributed in the composite with microcrack structure. The formation of hydroxyapatite（HA） on the composite in simulated body fluid（SBF） was analyzed by scanning electron microscopy（SEM）, energy dispersive spectroscopy（EDS）, X-ray diffraction（XRD）, and Raman spectra. Rod-like HA crystals deposit on the surface of PLLA/bioactive glass composite after soaking for 3 d. Both rod-like crystals and HA layer form on the surface for 14 d in SBF. The high bioactivity of PLLA/bioactive glass composite indicates the potential of materials for integration with bone.
作者 周智华 阮建明 邹俭鹏 周忠诚 申雄军
机构地区 State Key Laboratory of Powder Metallurgy
出处 《中国有色金属学会会刊：英文版》 EI CSCD 2007年第2期394-399,共6页 Transactions of Nonferrous Metals Society of China
基金 Project(50174059) supported by the National Natural Science Foundation of China
关键词 玻璃 聚乳酸 生物可再吸收性 复合材料 生物活性 bioactivity composite bioactive glass poly-L-lactide
分类号 R318.08 [医药卫生—生物医学工程]
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参考文献26

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同被引文献75

  • 1Yukiko Nakahara,Dwight Xuan.Study on the optical property and biocompatibility of a tissue engineering cornea[J].International Journal of Ophthalmology(English edition),2012,5(1):45-49. 被引量：3
  • 2张海坡,阮建明,周忠诚,李亚军.Preparation of monomer of degradable biomaterial poly(L-lactide)[J].Journal of Central South University of Technology,2005,12(3):246-250. 被引量：2
  • 3李俊杰,姚晖,陈亦平,柏金根,马军阳,姚康德.微纳米羟基磷灰石及其复合材料研究进展[J].化工进展,2006,25(6):651-657. 被引量：22
  • 4王华林,戴静,翟林峰,左金平.可降解聚乳酸/骨粉杂化材料的制备与降解性能[J].高分子材料科学与工程,2007,23(3):167-170. 被引量：6
  • 5周智华,阮建明,邹俭鹏,周忠诚,申雄军.Synthesis and structural characterization of macroporous bioactive glass[J].Journal of Central South University of Technology,2007,14(3):301-304. 被引量：1
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  • 9LI Ya-jun, RUAN Jian-ming. Study on the biodegradation of poly (d,l-lactide)/hydroxyapatite porous composite[J]. Journal of Central South University of Technology: Natural Science, 2007, 38(3): 433-437.
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引证文献5

二级引证文献12

中国有色金属学会会刊：英文版
2007年 第2期

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