摘要
目的探讨老年人造影剂肾病（RCN）的发生率并对相关的危险因素进行分析。方法比较造影剂肾病患者与未发生造影剂肾病患者的基础疾病、临床特点、造影当日静脉液体入量、基础肾功能水平，探讨造影剂肾病发生的危险因素。结果60岁以上人群发生率为11．52％，明显高于30～59岁人群；合并冠心病、高血压、糖尿病的患者RCN的发生率增加；合并肾功能不全的患者RCN的发生率可达54．8％；RCN患者液体入量远远低于未发生RCN的患者。结论老年人造影剂肾病的发生率很高，可能与肾脏贮备能力降低有关；充分水化是防止造影剂肾病发生的有效方法。
Objective To explore the incidence and possible risk factors of RCN in old patients by retrospective analysis. Method We compared the difference of fundamental diseases, clinical features, basic renal function and volume of intra-venous fluid received on operation day between the patients with and without RCN by retrospective analysis, in order to investigate the possible risk factors of RCN. Results According to our study, we found that the occurence of RCN in elderly（≥60 years） were 11.52%, which was much higher compared with the people aged 30～59 who had received angiography at the same period in our hospital（P〈0. 05）. We also found if coronary artery disease, hypertension and diabetes mellitus were concomitantly seem in one patient, the risk of RCN would increased, RR = 1. 538; if patient also compicated with renal function insufficiency the incidence of RCN increased sharply to 54. 8 % （P〈0. 05）. Hydration status were also different in two group： RCN people had received only 700 ml fluid on operation day which was much less than those in non-RCN people （P〈0. 05）. Conclusions The incidence of RCN is much higher in people over 60-year-old. Such condition may be partly caused by decreasing renal reserve capacity with aging and in association of coronary artery disease and diabetes mellitus. Sufficient hydration is an effective way to prevent RCN in elderly as well as in other people.
出处
《临床肾脏病杂志》
2007年第2期67-68,共2页
Journal Of Clinical Nephrology
关键词
老年
造影剂肾病
水化
Elderly
Radiographic Contrast Nephropathy
Hydratation
