1,6-二磷酸果糖辅助治疗婴幼儿肺炎并心衰对心肌肌钙蛋白I的影响被引量：2

Therapeutic effect of fructose 1,6 diphosphate (FDP) in infants suffering pneumonia with heart failure

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摘要目的：观察1，6-二磷酸果糖（FDP）辅助治疗婴幼儿肺炎并心力衰竭时对心肌肌钙蛋白Ⅰ的影响。方法：124例心力衰竭患儿随机分成治疗组和对照组，每组62例。两组均给予常规抗感染、西地兰强心、利尿、扩管降低肺动脉高压、供氧等处理，治疗组在此基础上加用1，6-二磷酸果糖0．2g／（kg·d）静脉滴注，每日1次，疗程3～5d。分别于入院时及治疗4d后检测血浆心肌肌钙蛋白Ⅰ（cTnⅠ）浓度和磷酸肌酸激酶同功酶（CK-MB）活性。结果：治疗后4d两组cTnⅠ和CK-MB均有不同程度的下降（P〈0．05）；治疗后治疗组cTnⅠ和CK-MB显著低于对照组（P〈0．05）。结论：1，6-二磷酸果糖辅助治疗肺炎并心力衰竭，能及早改善患儿呼吸功能，纠正患儿心力衰竭。 Objective： To observe the therapeutic effect of fructose 1,6 diphosphate （FDP） in infants suffering pneumonia with heart failure. Methods： 124 cases were divided randomly into two groups, 62 cases in each group. Besides the routine treatment, the treatment group were treated with FDP 0.2 g/（kg·d） ,iv drip, qd. The cTnⅠ and CK-MB were measured at the first day and four days later. Results： The plasma concentration of cTnⅠ and CK-MB in both two groups 4d after treatment decreased in different extent （P〈 0.05） ; the plasma concentration of cTnⅠ and CK-MB in treatment group were much lower than that in control group （P〈0.05）. Conclusion： FDP was effective in treating pneumonia with heart failure.

作者张焯文

机构地区合肥医学院第五附属珠海医院儿科

出处《海南医学院学报》 CAS 2007年第1期21-22,27,共3页 Journal of Hainan Medical University

关键词 1 6-二磷酸果糖心肌肌钙蛋白肺炎心力衰竭充血性儿童 Fructose 1,6 Diphosphate cTnⅠ Pneumonia Heart Failure, congestive Infant

分类号 R722.13 [医药卫生—儿科]

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