摘要
目的观察ME方案在高三尖杉酯酶加阿糖胞苷（HA）或柔红霉素加阿糖胞苷（DA）化疗未达完全缓解（CR）的老年急性髓系白血病（AML）患者的疗效，并与传统方案进行比较。方法对诊断明确者随机分为ME治疗组和HA或DA治疗组，ME组1个疗程后，HA或DA组2个疗程后评价疗效。结果ME组CR率为75．0％，总有效率为85％，HA或DA组1个疗程后CR率分别为33．3％、30．0％，总有效率分别为55．6％、50．0％。两组相比ME方案的骨髓抑制作用强于HA或DA方案，而非造血系统不良反应差异无统计学意义。结论ME方案对老年急性髓系白血病的疗效显著优于HA、DA方案，可作为老年急性髓系白血病的诱导治疗方案。
Objective To observe the effect of ME in the cases of aged AML who didnt obtain CR after the treatment of HA or DA. Methods The patients were randomly divided into two groups. One was treated with ME, the other with HA or DA. The effects of the two groups were compared after one time of therapy with ME and two times of therapy with HA or DA. Results The CR rate of ME group was 75.0%. It was obviously more than the rate of HA or DA group. Conclusion The effect of ME in the cases of old AML is better than that of HA or DA group.
出处
《中原医刊》
2007年第9期15-16,共2页
Central Plains Medical Journal
关键词
白血病
急性
老年人
诱导化疗
Leukemia, acute
The eldly
Inductive treatment
