摘要
目的探讨地尔硫[艹卓]对急性心肌梗死（AMI）急诊冠脉介入治疗（PCI）中并发的无再流现象的影响。方法对我院2003年6月至2006年8月行急诊冠脉介入治疗的106例AMI病人,随机分为两组,对照组54例、治疗组52例。两组均在PCI前30 min嚼服阿司匹林300 mg及氯吡格雷300 mg,对照组在PCI术中持续静脉滴注硝酸甘油10-20μg/min,治疗组在PCI术中持续静脉滴注地尔硫[艹卓]10-20μg/min,球囊扩张前冠脉内给地尔硫[艹卓]0.2 mg/次。结果对照组发生无再流6例（11.1%）,其中发生心血管崩溃死亡1例。治疗组发生无再流1例（1.9%）,无死亡病例,两组对比差异有统计学意义（P〈0.01）。结论地尔硫[艹卓]能有效防治AMI急诊冠脉介入治疗中的无再流的发生。
Objective To evaluate effects of diltiazem on no - reflow during emergency percutaneous coronary intervention （PCI） for acute myocardial infarction （AMI）. Methods One hundred and six patients with AMI of persuing PCI were randomly divided into two groups,control group 54 patients ,diltiazem treated group 52 patients. Two groups used aspilin 300 mg and clopidogrel 300 mg befor PCI, the control group ivdriped constantly nitroglycerin 10 -20 μg per rain during PCI,diltiazem -treated group ivdriped diltiazem 10 -20 μg per min during PCI. Results Six cases （ 11.6% ） developed no - reflow in control group , One case dead from cardiovascular collapse, 1 case （1.9%） developed no -reflow in diltiazemtreated group. There was statistial difference between the both groups （P 〈 0.01 ）. Conclusion Diltiazem is useful to prevent and treat no -reflow during PCI for AMI.
出处
《中原医刊》
2007年第7期31-32,共2页
Central Plains Medical Journal
关键词
急性心肌梗死
冠状动脉介入治疗
地尔硫革
无再流
Acute myocardial infarction
Percutaneous coronary intervention
Dihiazem
No - reflow
