1M Rossignol,A Leclerc,P Hilliquin,et al.Primary osteoarthritis and occupations:A national cross sectional survey of 10 412 symptomatic patients.Occupations and Environmental medicine[J].London,2003,60(11):882.
5M M Haara,P Manninen,H Kroger,et al.Osteoarthritis of finger joints in Finns aged 30 or over:Prevalence,determinants,and ssociation with mortality[J].Ann Rheum Dis 2003,62(2):151.
6Spector TD,Hart DJ,Doyle DV.Incidence and progression of osteoarthritis in women with unilateral knee disease in the general population:the effect of obesity[J].Ann Rheum Dis,1994,53:565-568.
7Bengt Jrvholm,Stefan Lewold,Henrik Malchau,et al.Age,bodyweight,smoking habits and the risk of severe osteoarthritis in the hip and knee in men[J].European Journal of Epidemiology Dordrecht,2005,20(6):537.
8Mark H,Ebell.Effect of Exercise Intensity on Osteoarthritis[J].American Family Physician Kansas City,Sep 1,2004,70(5):865.
9Kujala UM,Kettunen J,Paananen H,et al.Knee osteoarthritis in former runers,soccer players,weight lifters and shooters[J].Arthritis Rheum,1995,38:539-546.
10Spector TD,Harris PA,Hart DJ,et al.The risk of osteoarthritis associated with long-term weight-bearing sports[J].Arthritis Rheum,1996,38:988-995.
2[1]Robert M, Ashok R,Steven B.The role of nitric oxide in inflammation and immunity[J].Arthritis Rheum,1998, 41:1 141～1 151.
3[2]Blanco FJ, Galdo F, de Toro FJ,et al. Osteoarthritis chondrocytes die by apoptosis, a possible pathwy for osteoarthritis pathology[J].Arthritis Rheum,1998, 41:284～289.
4[3]Cao M, Evans CH, Stefanovic-Racic M,et al. Nitric oxide inhibits the synthesis of the Ⅱ collagen without altering Col2A1 mRNA abundance prolyl hydroxylase as a possible target[J]. Biochem J, 1997, 324: 305～310.
5[4]PelletierJ-P, Jovanovic D, Julio C. Reduced progremkm ofexperimental ooteoarthritis in vivo by salective inhibition ofinducible nitric oxide synthase[J]. Arthritis Rheum, 1998,41:1 275～ 1 286. ~
6[5]Sanshiro HashimotO, Kenji Takahashi, David Aiel, et al.Chondrocyte apopto~ and nitric oxide production duringexperimentallyinduced osteoarthritis[J ]. Arthritis rheum,1998, 41:1 266～ 1 274.
7[6]Panasiuk AF, Laroshuk GV, MIuovich D. Effect of freeradicals on proliferation and metaboli~m of chondrocytes andon sensitivity of a cellular monolayer to proteases[J]. VoprM~d Khim, 1995, 41:19～22.
8[7]Schiller J, Arnhold J, Schwinn J, et al. Reactivity of car~l~eand selected carbohydrates with hydroxyl radicals:an NMRstudyto detect degradation products[J]. Free Radic Res,1998, 28:215～218.
9Felson DT. Epidemiology of hip and knee osteoarthrithis(Review).Epidemiol Rve, 1998,10 : 1-28.
10Felson DT, Naimark A, Anderson J, et al. The prevalence of knee osteoarthritis in the elderly: the Framingham Osteoarthritis Study.Arthritis Rheum, 1987, 30:914-918.
