摘要
以刚性的石胆酸甲酯为骨架,手性不对称脲为侧链,通过三光气桥连,设计合成了一类新型的手性分子裂缝.7个分子裂缝均为新化合物,其结构均经1HNMR,IR,MS和元素分析确证,并且考察了其对卤素阴离子Cl-,Br-,I-的识别性能.初步的实验结果表明,这类分子裂缝不仅可与所考察的卤素阴离子形成1∶1型超分子配合物,而且对卤素阴离子具有良好的识别选择性.
A novel type of chiral molecular clefts has been designed and synthesized by linking a chiral unsymmetrically disubstituted urea to rigid methyl lithocholate via triphosgene. Seven molecular clefts are new compounds. Their structures were confirmed by ~H NMR, IR, MS spectra and elemental analyses. The recognition properties of these molecular clefts for halogen anions have been investigated by UV-visible spectral titration. The preliminary results indicated that these molecular clefts not only possessed the ability to form 1 ： 1 complex with anions examined, but also showed good selectivity for halogen anions.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2007年第4期513-518,共6页
Chinese Journal of Organic Chemistry
基金
西南民族大学自然科学基金重点(No.05NZ002)资助项目.
关键词
石胆酸
分子裂缝
合成
手性不对称脲
lithocholic acid
molecular cleft
synthesis
chiral unsymmetrical urea
