期刊文献+

牛MC1R基因——新的SNP 被引量:2

A New SNP in MC1R Gene of Cattle
在线阅读 下载PDF
导出
摘要 本实验克隆测序了中国荷斯坦牛、鲁西黄牛和渤海黑牛三个品种的MC1R基因。运用Blastn工具对本实验得到的序列及所有发表的牛MC1R基因序列进行比对分析,发现牛MC1R基因编码区725bp处存在一新的单核苷酸多态性(SNP)。基于此SNP我们对现发表的所有牛MC1R基因做了总结。 The sequences of MC1R gene of Chinese Holstein Cattle,Luxi Yellow Cattle and Bohai Black Cattle were cloned and sequenced in this experiment.We analyzed the sequences which we had sequenced and which had been pubilcized by tools of Blastn.We found a new SNP (MC)(Single Nucleotide Polymorphism)at 725 position of the MC1R gene coding region.We made a summary about the MCIR gene of cattle which had been publicized base on this SNP.
出处 《中国奶牛》 2007年第4期6-7,共2页 China Dairy Cattle
关键词 牛MC1R基因 SNP 中国荷斯坦牛 鲁西黄牛 渤海黑牛 MC1R gene of catfle SNP Chinese Holstein Catfle Luxi Yellow Catfle Bohai Black Cattle
  • 相关文献

参考文献7

  • 1Maydet C,Taberlet P.Holstein's milk detection in cheeses inferred from Melanocortin Receptor l(MC1R)gene polymorphism[J].Dary Sci,2002,85:707-715.
  • 2杨永升,李宁,邓学梅,吴常信.黑素皮质素受体1——哺乳动物黑色素形成中的关键基因[J].遗传,2004,26(4):544-550. 被引量:35
  • 3Klungland H,Vage DI,Gomez-Raya L,Adalsteinsson S,Lien S.The role of melanocyte -stimulating hormone (MSH)receptor in bovine coat color determination[J].Mammalian Genome,1995,6:636-639.
  • 4Mirko V,Christiance S,Wolfgang M,Volker H.Molecular cloning of a bovine MSH receptor which is high expressed in the testis[J].Febs Letters,1994,248:268-272.
  • 5Engle L J,Simpson C L,Landers J E.Using high -throughput SNP technologies to study cancer[J].Oncogene,2006,25(11):1594-601.
  • 6Cantor C R.The use of genetic SNPs as new diagnostic markers in preventive medicine[J].Ann N Y Acad Sci,2005,1055:48-57.
  • 7侯君,谭云山,韩琼林.3种常用单核苷酸多态性检测方法的应用比较[J].中国临床医学,2004,11(2):255-257. 被引量:4

二级参考文献7

  • 1Daly A K. Candidate gene case- control studies. Pharacogenomicc, 2003, 4(2): 127-139.
  • 2Jain K K. Personalized medicine. Curr Opin Mol Ther, 2002, 4(6): 548-558.
  • 3Fischer S G, Lerman L S. DNA fragments differing by single base- pair substitutions are separated by denaturing gradient gels: correspondence with melting theory. Proc Natl Acad Sci USA, 1983, 80(6) :1579-1583.
  • 4Sheffield V C, Beck J S, Kwitek A E, et al. The sensitivity of single - strand conformation polymorphism analysis for the detection of single base substitutions. Genomics, 1993, 16(2): 325-332.
  • 5JosephS DavidWR 黄培堂 译.分子克隆实验指南(第3版)[M].北京:科学出版社,2002.96-99.
  • 6ShiP,LuXM.Melanocortin-1 receptor gene variants in four Chinese ethnic populations[J].Cell Research,2001,11(1):81-84. 被引量:11
  • 7吕雪梅,施鹏,张亚平.肤色、黑色素皮质素受体1和紫外线[J].遗传,2002,24(5):563-570. 被引量:9

共引文献37

同被引文献58

引证文献2

二级引证文献42

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部