摘要
目的研究社区获得性金黄色葡萄球菌耐药情况。方法采用常规方法分离金黄色葡萄球菌,用全自动微生物分析仪进行菌种鉴定和药敏试验,采用苯唑西林纸片扩散法检测耐甲氧西林金黄色葡萄球菌(MRSA)。结果社区感染的金黄色葡萄球菌主要分离自精液和尿液,MRSA的分离率为22.0%。MRSA对青霉素和环丙沙星的耐药率均为100%。所有的分离株对呋喃妥因和万古霉素均敏感。MRSA对红霉素、庆大霉素、四环素、复方新诺明、氯霉素和头孢克罗的耐药率分别为92.6%、33.3%、67.7%、92.6%、82.1%和75.1%。MSSA对上述药物的耐药率为75.6%、32.3%、50.5%、7.1%、25.3%和4.5%。结论社区感染的金黄色葡萄球菌主要为甲氧西林敏感的金黄色葡萄球菌,社区感染的MRSA的耐药性较为严重,而MSSA除青霉素和红霉素外耐药率较低。万古霉素对MRSA的体外抗菌活性非常强。
Objective To investigate the antimierohial-resistant profile of community-acquired Staphylococcus aureus isolated from clinical specimens. Methods The isolates of Staphyloedccus aureus were isolated from clinical specimens by routine methods. The identification and suseeptihility test of the isolates were determined by Automated Mierohiology Analyzer. Disk-diffusion was used for detecting methieillin-resistant Staphylococcus aureus, MRSA. Results The isolates were mainly isolated from sperms and urines. 22.0% of isolates were referred as MRSA. All isolates of MRSA were resistant to Penicillin G and Ciofloxaein. All isolates were susceptible to Nitrofurantoin and Vaneomyein. The resistant rates of the isolates of MRSA to Erythromyein, Gentamyein,Tetraeyeline, Suffamethoxazole and Chloramphenieol were 92.6%, 33.3%, 67.7% ,92.6% ,82.1% and 75.1%, respectively, those of MSSA were 75.6% ,32.3% ,50.5% ,7.1% ,25.3% and 4.5%, respectively. Conclusions Most of Community-acquired Staphylococcus aureus are MSSA. The antimierobiol-resistanee of MRSA is serious, but the antihioties have high activity to the isolates of MSSA with the exception of Penicillin G and Erythromyein in vitro. Vaneomyein has very high activity to the isolates of MRSA in vitro.
出处
《中国微生态学杂志》
CAS
CSCD
2007年第2期207-208,共2页
Chinese Journal of Microecology
关键词
金黄色葡萄球菌
抗菌素
耐药性
社区感染
Community-acquired Staphylococcus aureus
Antihioties
Antimierobial-resistanee
Community-acquired
