摘要
目的:评价无偿献血HEV筛查的必要性和选择适当的方法。方法:使用抗-HEV IgG和抗-HEV IgM检测方法对绍兴市2005年6月至2006年5月3 701份街头无偿献血标本进行检测,对阳性标本进行RT-PCR确认是否为病毒血症。结果:3 701份标本抗-HEV IgG和抗-HEV IgM阳性率分别为29.91%和1.35%,与RT-PCR的阳性符合率分别为0.45%和12.00%。结论:在目前献血人群中确实存在HEV病毒血症,有必要增加相应的检测项目,抗-HEV IgM检测相比抗-HEV IgG检测更适合作为无偿献血人群的HEV筛查方法。
Objective： To evaluate the necessity of HEV screening in volunteer blood donor and to select an appropriate method. Methods：Anti -HEV- IgG and anti-HEV -IgM were detected in the 3 701 blood samples of donors collected in the street from July 2005 to May 2006. The HEV - antibody positive samples were verified by RT -PCIL Results：29. 9% of 3 701 blood samples were anti - HEV IgG positive, while only 1.35% were anti - HEV IgM positive. The coincidence with RT - PCR results was 0. 45% and 12. 00% respectively. Conclusion：There does exist HEV viremia in some volunteer blood donors and it is necessary to add HEV detection to routine screening items. Furthermore, anti - HEV IgM is more appropriate as a screening item than anti- HEV IgG.
出处
《中国卫生检验杂志》
CAS
2007年第4期669-670,共2页
Chinese Journal of Health Laboratory Technology
基金
绍兴市科技项目(2005198)
关键词
戊型肝炎病毒
无偿献血
筛查
Hepatitis E virus
Volunteer blood donation
Screening
