摘要
目的通过MRI测量正常对照组和Graves眼病组的眼外肌、眶内侧脂肪厚度及T2弛豫时间,探讨MRI在Graves眼病诊断、指导临床分期及判断疗效方面的价值。资料与方法正常对照组25名50只眼;Graves眼病组30例,均为双侧突眼,共60只眼,行眼眶MRI扫描。分别测量眼球突出值、眼外肌短径及长径并计算短径与长径的比值(R值),测量球内侧脂肪厚度,根据SE双回波T2WI测得眼肌及球后脂肪的T2弛豫时间。结果(1)病变组眼球突出值明显大于正常对照组,差异有统计学意义(P<0.01)。(2)病变组各眼外肌短径均明显大于正常对照组,差异有统计学意义(P<0.01);除下直肌外,病变组其余眼外肌的长径与正常对照组差异无统计学意义(P>0.05)。病变组眼肌的R值均明显大于正常对照组,两组之间差异有统计学意义(P<0.01)。(3)病变组球内侧脂肪的厚度明显大于正常对照组,两组之间差异有统计学意义(P<0.01)。(4)病变组与正常对照组之间眼外肌的T2值差异有统计学意义(P<0.01或0.05);而球后脂肪T2值差异无统计学意义(P>0.05)。结论MRI眶内组织的定量测定对Graves眼病的诊断、指导临床分期、判断疗效有一定的帮助。
Objective To quantitatively measure the values of exophthalmoscs, short and long diameters of extraocular muscles, the thickness of fatty tissue at the inner side of eye ball, and the T2 values of extraocular muscles and fat tissue both in normal groups and Graves Ophthalmopathy （GO） patients, in order to evaluate the MRI values in the diagnosis, clinic stages, and curative effect of Graves Ophthalmopathy. Materials and Methods 25 normal cases （50 eyes） and 30 cases of Graves Ophthalmopathy （double sides, totally 60 eyes） were included in this study. All the cases were performed MRI orbital scan. The short and long diameters of extraocular muscles were measured on TtWI axial or coronal images. The ratios of short diameter to long diameter （R values） of extraocular muscles were calculated. The thickness of fatty tissue at the inner side of eyeballs and the values of exophthalmos were also measured. At the same time, the T2 values of extraocular muscles and the orbital fatty tissue were measured in the SE dual echo images. Results （ 1 ） The exophthalmos value of GO group was larger than that of normal group. There was significant difference between these two groups in exophthalmos value （ P 〈 0.01 ） . （2） The short diameter of extraocular muscles in GO group was larger than that in control group. There was significant difference between these two groups in the short diameter of extraocular muscles （ P 〈 0.01 ）. There was no significant difference between this two groups in the long diameter of extraocular muscles （P 〉 0.05）. The R-value of extraocular muscles in GO group was larger than that in control group. There was statistical difference between the GO group and control group in the R-values of extracular muscles. （3） The thickness of fatty tissue at the inner side of eye balls in GO group was larger than that in control group. There was significant difference （ P 〈 0.01） . （4） There were statistically differences between GO group and control group in the T2 values of extraocular muscles （ P 〈 0.01 ）, but there was no statistically difference in fat tissue between these two groups （ P 〉 0.05）. Conclusion MRI quantitative analysis of orbital structures is helpful in the diagnosis, clinic stages, and curative effect of Graves Ophthalmopathy.
出处
《临床放射学杂志》
CSCD
北大核心
2007年第4期336-340,共5页
Journal of Clinical Radiology
关键词
GRAVES眼病
眼球突出
磁共振成像
眼外肌
横向弛豫时间
Graves Ophthalmopathy Exophthalmos Magnetic resonance imaging Extraocular muscles Transverse relaxation time
