摘要
目的研究和评价CA125、CA153、CEA在结核性及癌性积液中的临床应用及检验效能。方法选结核性积液患者92例,癌性积液患者32例,采用化学发光免疫法检测胸腹水及血清中的CA125、CA153、CEA。结果恶性积液患者积液及血清的CA125、CA153、CEA含量均明显增高,且CA153、CEA明显高于结核性者,而两者间CA125的差异无显著性,积液中的CA125、CA153、CEA含量明显高于血清中的CA125、CA153、CEA含量。结论单一检测肿瘤标志物CA125,检验效能差,特异性差,而与CA153、CEA联合检测提高了敏感性和特异性,应强调多种标志物的联合检测及动态观察。
Objective To study the diagnostic value and effectiveness of co - detections of CA125, CEA and CA153 in serum and pleural effusion. Methods 92 eases of tubercular perfusion and 32 eases of malignant perfusion, CA125, CA153 and CEA in serum and pleural effusion were detected by chemical luminal immunology. Results Levels of CA125, CA153 and CEA in serum and effusion of malignant tumor were heavily high, and CA153 and CEA were significantly higher than that of tuberculosis. Nonetheless CA125 was same between the two groups. The level of perfusion of the three markers was higher than that of serum. Conclusion Sensitivity and specificity of simple CA125 to detect tuberculosis and malignant tumor are not as good as eodeteetion of the three tumor markers with timely observations.
出处
《临床肺科杂志》
2007年第5期478-479,共2页
Journal of Clinical Pulmonary Medicine
